4. Erickson P, Gardner LD, Loffredo CA, St. George DM, Bowman ED, Deepak J, Mitchell KA, Meaney CL, Langenberg P, Bernat D, Am S., Ryan B.M. Racial and Ethnic Differences in the Relationship Between Aspirin Use and Non-Small Cell Lung Cancer Risk and Survival, Cancer Epidemiology, Biomarkers & Prevention, doi: 10.1158/1055-9965.EPI-18-0366., PMID: 30171037
3. Nichols N, Mitchell KA, Zingone A, Meaney C, Bowman ED, Ryan BM. Relationship between the TP53 SNP rs1800371 and Lung Cancer in African Americans, Cancer Health Disparities, doi:10.9777/chd.2018.10016.
2: Houston KA, Mitchell KA, King J, White A, Ryan BM. Histologic Lung Cancer Incidence Rates and Trends vary by Race/Ethnicity and Residential County. J Thorac Oncol. 2018 Jan 19. pii: S1556-0864(18)30003-0. doi: 10.1016/j.jtho.2017.12.010. [Epub ahead of print] PubMed PMID: 29360512.
1: Mitchell KA, Zingone A, Toulabi L, Boeckelman J, Ryan BM. Comparative Transcriptome Profiling Reveals Coding and Noncoding RNA Differences in NSCLC from African Americans and European Americans. Clin Cancer Res. 2017 Dec 1;23(23):7412-7425. doi: 10.1158/1078-0432.CCR-17-0527. PubMed PMID: 29196495.
Currently, the IT LAB studies the causes and consequences of cancer health disparities according to race, sex, and age.
We are trying to figure out why:
1. African Americans get, and die from, lung and kidney cancer more than any other racial group in the country, even though they smoke less.
2. young American women get lung cancer more than young American men, even though they smoke less.
3. adolescent and young adult (AYA) cancer patients (ages 15-39) have a different tumor biology than children or older adults.
The IT LAB uses biological, environmental, and social clues to try and solve these important health problems. You can find out more about our research here.
Health disparities are significant differences in health outcomes between a specific population when compared to the general population.
The National Cancer Institute defines cancer health disparities as adverse differences in cancer incidence (new cases), cancer prevalence (all existing cases), morbidity (cancer-related health complications), cancer mortality (deaths), cancer survivorship, and burden of cancer or related health conditions that exist among specific population groups in the United States.
Watch the video below to learn more about cancer health disparities.