Dethoff, Liz

A.B.: Chemistry in 2005

Ph.D.: Physical Chemistry with Hashim Al-Hashimi at the University of Michigan in 2011

Post-doc: Biological Chemistry with Kevin Weeks at the University of North Carolina

scientist: ribometrix, inc in chapel hill, NC

Publications

  • “Pervasive tertiary structure in the dengue virus RNA genome.” E.A. Dethoff, M.A. Boerneke, N.S. Gokhale, B.M. Muhire, D.P. Martin, M.T. Sacco, M.J. McFadden, J.B. Weinstein, W.B. Messer, S.M. Horner and Kevin M. Weeks, Proc. Nat. Acad. Sci., 2018, 115, 11513.
  • “Packaged and free Satellite Tobacco Mosaic Virus (STMV) RNA genomes adopt distinct conformational states.”  B.C. Larman, E.A. Dethoff and K.M. Weeks, Biochem. 2017, 56, 2175.
  • “Dynamic motions of the HIV-​1 frameshift site RNA.”  K. Mouzakis, E.A. Dethoff, M. Tonelli, H. Al-Hashimi and S.E. Butcher, Biophys. J. 2015, 108, 644.
  • “Invisible RNA state dynamically couples distant motifs.”  J. Lee, E.A. Dethoff and H.M. Al-Hashimi, Proc. Nat. Acad. Sci. 2014, 111, 9485.
  • “Visualizing transient low-populated structures of RNA.” E.A. Dethoff, K. Petzold, J. Chugh, A. Casiano-Megroni and H.M. Al-Hashimi, Nature, 2012, 491, 724.
  • “Functional complexity and regulation through RNA dynamics.”E.A. Dethoff, J. Chugh, A.M. Mustoe and H.M. Al-Hashimi, Nature, 2012, 482, 322.
  • “A rare example of lock-and-key RNA recognition.” E.A. Dethoff and H.M. Al-Hashimi, J. Molec. Bio., 2010, 404, 553.
  • “Furan approach to Vitamin D analogues. Synthesis of the A-ring of calcitriol and 1α-hydroxy-3-deoxyvitamin D3.” W.H. Miles, K.B. Connell, G. Ulas, H.H. Tuson, E.A. Dethoff, V. Mehta and A.J. Thrall, J. Org. Chem. 2010, 75, 6820.
  • “Variable helix elongation as a tool to modulate RNA alignment and motional couplings.” E.A. Dethoff, A.L. Hansen, Q. Zhang, H.M. Al-Hashimi, J. Mag. Res., 2010, 202, 117.
  • “Characterizing complex dynamics in the transactivation response element apical loop and motional correlations with the bulge by NMR, molecular dynamics, and mutagenesis.” E. A. Dethoff, A. L. Hansen, C. Musselman, E. D. Watt, I. Andricioaei and H. M. Al-Hashimi, Biophysical Journal 2008, 95, 3906.
  • “Kishner’s reduction of 2-furylhydrazone gives 2-methylene-2,3-dihydrofuran, a highly reactive ene in the ene reaction. ” W. H. Miles, E. A. Dethoff, H. H. Tuson, and G. Ulas, J. Org. Chem. 2005, 70, 2862.