Principal Investigator

Michael A. Bertucci

Associate Professor of Chemistry

Michael graduated from Stevens Institute of Technology with B.S. in Chemical Biology before pursuing his Ph.D. in Chemistry at the University of North Carolina at Chapel Hill.  Under the mentorship of Dr. Michel R. Gagné, he investigated methods for derivatizing N-Acyl Homoserine Lactone (AHLs), key signaling molecules in gram-negative bacterial quorum sensing. He joined the chemistry department at Hartwick College as a Visiting Assistant Professor in 2014 before moving to Moravian University one year later.  In 2021, he accepted an offer to join the chemistry department at his current institution, Lafayette College, and was promoted to Associate Professor with Tenure in 2024.  He has taught courses in Organic Chemistry I & II, Bioorganic & Medicinal Chemistry, Synthetic Organic Chemistry, Nursing Chemistry and Senior Seminar for Chemistry and Biochemistry Majors.  He is the recipient of an NSF CAREER award and was named a Henry Dreyfus Teacher-Scholar in 2023.

Michael A. Bertucci’s Curriculum Vitae (CV)

Current Group Members

Mallory Downs

Senior Neuroscience Major

My research focuses on the synthesis and purification of the competence-stimulating peptide (CSP) of Streptococcus gordonii. I am performing alanine substitutions in order to determine if this changes the quorum sensing ability of the bacteria.

 

Braeden Beal

Senior Chemistry Major

My research focuses on finding more efficient ways to synthesize the MeDbz linker and LamD derivatives to be utilized in the bacteria Lactobacillus plantarum, as well as studying the stability of these synthesized LamD derivatives.

 

Alex Yurtola
he/him

Junior Chemistry Major

My research focuses on developing and optimizing a method of measuring beta-glucuronidase activity in an assay to determine the effect of synthetic peptides on quorum sensing in Lactobacillus plantarum.

 

Sydney Weibel

Senior Biology Major

My research is in collaboration with the Mensch Lab studying the environmentally relevant interactions between the bacteria Bacillus subtilis, polystyrene nanoparticles, and the agricultural antibiotic Tylosin.  I use growth based viability assays to determine bacterial viability at different concentrations and combinations of these pollutants.

 

Jack Baum

Junior Biology Major

My research focuses on synthesizing the plasmid PLIP404-3 to transform into Lactiplantibacillus plantarum in order to create an effective reporter strain with which to test the lab’s peptides.

 

 

Katelyn Golembiewski

Sophomore Biochemistry Major

My research focuses on assembling and optimizing reporter plasmids for quorum sensing in Lactiplantibacillus plantarum.

 

 

Michaela McCusker

Sophomore Biochemistry Major

My current research is centered around the finding and optimizing of efficient procedures for transforming DNA plasmids into Lactiplantibacillus plantarum and Lactococcus lactis.   

Former Group Members

Allie Campanella ’24 – Memorial Sloan Kettering

Xiaotian Gong ’24 – University of Wisconsin-Madison

Abby Skidmore ’24 – Children’s Hospital of Philadelphia

Ryann Carlotz ’24

Brianna Leopold ’23 – Pfizer

Becky Hartman ’23 – UMass Amherst

Jasmine Nguyen ’23 – UC Irvine/Tufts University

Elizabeth Jones ’23  – University of Central Florida

Michael Gorgan ’22 – University of Connecticut

Jillian Kopchak ’22 – Avantor

Joelis Rodriquez-Santos ’22

Zachary Filliben ’22 – Florida Atlantic University

Fadi Hanna ’21 – Rowan University School of Osteopathic Medicine

Emilee Engler ’21 – DSM

Naomi Rieth ’21 – OraSure Technologies

Gabe Chlebove ’21 – OraSure Technologies

Liz Hutnick ’21 – NMS Labs

Alec Buttner ’21 – University of Chicago

Ashlyn Cantrel ’19 – University of Delaware/Yale University

Jonathan Nadraws ’19 – University of Pennsylvania

Kylie Chichura ’19 – Syracuse University

Robert Hillman ’18 – University of Delaware/Chemours

Erin Tiwold ’17 – GlaxoSmithKline

Jessica Lynch ’17 – University of Tennessee School of Veterinary Medicine

Jonathan Le ’17 – Temple University School of Dentistry

Daniel Schmucker ’16 – Trinity Consultants