Topic 1: Papers


200- Describe the 3 levels of folding?

Primary- sequence of nucleotides Secondary- base pair bonds (double helix)
Tertiary- folding

400- What is chromatin?

It is RNA/DNA and proteins


600- how does chromatin affect gene expression?


Heterochromatin is tightly packed and the genes are not expressed.
Euchromatin is loosely packed and the genes are expressed.

800- RNA silencing and genome regulation article- what is a transposon?


Selfish DNA entity capable of using a genome as an ecosystem where it can survive and proliferate

Topic 2: Lecture


200- What is ssRNAase?


Enzyme that degrades single stranded RNA

400- What is the central dogma of genetics?

(DNA)
DNA->transcription->RNA->translation->protein

600-Does mature mRNA have introns?


NO

800- What are two ways to crosslink RNA and proteins?


UV and formaldehyde

Topic 3: Genomics

200- What does Dr. Gregory use genomics to study?


Ds/ssRNA  and secondary structure

400- What is splicing?

Removing introns, non coding regions

600- What is secondary structure?

Base pair linkage

800-(1000)- RNA binding domains bind to _______ or _______.


A sequence or a structure.

Topic 4: Interesting Facts


200- Where is Dr Gregory from?

Phoenix, Arizona

400- What is one subject we should all take before graduating?

Computer programming

600-What do you do about mutation rates in the study of genomics?

You ignore them.

800- What career do you think Dr. Gregory thinks we need more of?

Bioengineering/computer engineering because processor speeds are not able to keep up with sequencing